8 Reasons Why Mastitis Treatments Fail


Various factors can lead to a failure of treatment of clinical mastitis cases and recurrent cases :

1. Characteristics of bacteria

Mastitis caused by certain bacteria can be more difficult to treat when compared to others. Those bacteria possess some mechanisms,(similar to a “carapace”), that protect them from the antimicrobials.

2. Choice of antimicrobial

It is important to know what type of organism is causing the infection as some antimicrobials have better action against Gram-positive bacteria (as Staphylococci and Streptococci) while others can be indicated against Gram-negative bacteria such as Escherichia coli.

3. Antimicrobial resistance

Antimicrobial resistance can be detected by in vitro antimicrobial sensitivity testing. Some organisms that are not bacteria such as yeast, have a natural resistance to antimicrobials.



4. Time of treatment

Although prompt treatment of clinical mastitis after the first symptoms increases the chance of cure, it is again very important to know what type of organism is causing the infection.

5. Dose, route, duration

Dose and route of administration and duration of treatment are crucial to follow the prescribed dose by the vet and recommended by the label.

6. History of mastitis

Treatments should be administered after the farmer has worked closely with their veterinarian, has reviewed the medical history of the cow and evaluated the chances for therapeutic success.

7. Immunity

Mastitis is a multi-factorial disease, which means that factors such as poor nutrition, inadequate vaccination, poor environment, and stress can contribute to immune suppression.

8. New infections

Precautions should be taken when treating cows to avoid introduction of bacteria through the intramammary injector which might result in new infections. 


Dairy farmers should work closely with their herd veterinarian to help develop treatment protocols, provide oversight for appropriate drug use and monitor the success of treatment.

[Source : www.farmanddairy.com]

Unisensor offers rapid testing solutions for the food security, and in particular, the detection of antibiotics in milk.

View Our Products